Molecular Evolution Activities
 

This is a comprehensive bibliography (under construction) of primary and secondary sources on the neutral theory of molecular evolution. It currently covers the period 1973-2001.

Author :

Epperson, B. K.;Li, T. Q.

Year :

1996

Title :

Measurement of genetic structure within populations using Moran's spatial autocorrelation statistics

Journal :

Proceedings of the National Academy of Sciences of the United States of America

Volume :

93

Issue :

19

Pages :

10528-10532

Date :

Sep 17

Short Title :

Measurement of genetic structure within populations using Moran's spatial autocorrelation statistics

Alternate Journal :

Proc. Natl. Acad. Sci. U. S. A.

Custom 2 :

ISI:A1996VJ20300099

Abstract :

Spatial structure of genetic variation within populations, an important interacting influence on evolutionary and ecological processes, can be analyzed in detail by using spatial autocorrelation statistics, This paper characterizes the statistical properties of spatial autocorrelation statistics in this context and develops estimators of gene dispersal based on data on standing patterns of genetic variation. Large numbers of Monte Carlo simulations and a wide variety of sampling strategies are utilized. The results show that spatial autocorrelation statistics are highly predictable and informative. Thus, strong hypothesis tests for neutral theory can be formulated. Most strikingly, robust estimators of gene dispersal can be obtained with practical sample sizes. Details about optimal sampling strategies are also described.

Notes :

Times Cited: 23 VJ203 PROC NAT ACAD SCI USA
 -- contributed by John Beatty, March 29, 2002