Molecular Evolution Activities
 

This is a comprehensive bibliography (under construction) of primary and secondary sources on the neutral theory of molecular evolution. It currently covers the period 1973-2001.

Author :

Ford, M. J.;Thornton, P. J.;Park, L. K.

Year :

1999

Title :

Natural selection promotes divergence of transferrin among salmonid species

Journal :

Molecular Ecology

Volume :

8

Issue :

6

Pages :

1055-1061

Date :

Jun

Short Title :

Natural selection promotes divergence of transferrin among salmonid species

Alternate Journal :

Mol. Ecol.

Custom 2 :

ISI:000081624800014

Abstract :

Transferrin is an iron-binding protein that plays an important role in iron metabolism and resistance to bacterial infection in a variety of organisms. A comparison of transferrin coding sequences from four salmonid species shows that the rate of evolution at nonsynonymous sites is significantly higher than the rate at synonymous sites, suggesting that positive natural selection for new alleles has played an important role in the evolution of transferrin in some salmon species. We hypothesize that the selective agent driving rapid divergence is interactions between host transferrin and the iron-scavenging proteins of pathogenic bacteria.

Notes :

Times Cited: 3 219UE MOL ECOL
 -- contributed by John Beatty, March 29, 2002