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| This is a comprehensive bibliography (under construction) of primary and secondary sources on the neutral theory of molecular evolution. It currently covers the period 1973-2001. |
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Author :
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Gillespie, J. H.
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Year :
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2000
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Title :
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The neutral theory in an infinite population
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Journal :
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Gene
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Volume :
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261
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Issue :
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1
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Pages :
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11-18
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Date :
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Dec 30
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Short Title :
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The neutral theory in an infinite population
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Alternate Journal :
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Gene
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Custom 2 :
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ISI:000166759700003
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Abstract :
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Selective substitutions at one locus induce stochastic dynamics at a linked neutral locus that resemble genetic drift even when the population size is infinite. This new stochastic force, which is called genetic draft, causes genetic variation at the neutral locus to decrease with population size and the rate of deleterious substitution to increase with population size. The fact that heterozygosities in natural populations are only weakly dependent on population size suggests that genetic draft may be a much more important stochastic force than genetic drift in natural populations. Some of the mathematical properties of genetic draft are explored. (C) 2000 Elsevier Science B.V. All rights reserved.
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Notes :
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Times Cited: 0
398MF
GENE
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| | -- contributed by John Beatty, March 29, 2002 |
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