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Author :
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Kimura, M.
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Year :
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1995
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Title :
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Limitations of Darwinian Selection in a Finite Population
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Journal :
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Proceedings of the National Academy of Sciences of the United States of America
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Volume :
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92
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Issue :
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6
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Pages :
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2343-2344
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Date :
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Mar 14
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Short Title :
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Limitations of Darwinian Selection in a Finite Population
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Alternate Journal :
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Proc. Natl. Acad. Sci. U. S. A.
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Custom 2 :
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ISI:A1995QM40800114
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Abstract :
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In a finite population, the rate at which favorable mutations at several loci can evolve simultaneously is limited by the reproductive capacity of the species and the effective population number. The number of such loci is given by n < - (N-e/2) ln(1 - L(T)), in which N-e is the effective population number and L(T) is the ''substitution load'' (roughly, the reproductive excess available for positive selection). If L(T) = 0.1, as seems reasonable for large mammals, n < 0.05N(e).
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Notes :
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Times Cited: 6
QM408
PROC NAT ACAD SCI USA
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| | -- contributed by John Beatty, March 29, 2002 |
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