Molecular Evolution Activities
 

This is a comprehensive bibliography (under construction) of primary and secondary sources on the neutral theory of molecular evolution. It currently covers the period 1973-2001.

Author :

Mukherjee, M.;Skibinski, D. O.;Ward, R. D.

Year :

1987

Title :

A simulation study of the neutral evolution of heterozygosity and genetic distance

Journal :

Heredity

Volume :

58

Issue :

Pt 3

Pages :

413-23

Short Title :

A simulation study of the neutral evolution of heterozygosity and genetic distance

Custom 3 :

87249898

Abstract :

This paper considers a statistical test of neutral theory which can be applied to allozyme variation in natural populations. Computer simulation is used to derive the theoretical relationship between genetic distance and heterozygosity under a variety of neutral models employing stepwise mutation. It is shown that the relationship between these variables is robust to variation in the parameters of the models, and that a test of neutral theory can therefore be derived. Applications of the test in the analysis of data from natural populations are discussed in the light of the simulation results.
 -- contributed by John Beatty, March 29, 2002