Author :
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Nakamura, T.;Suyama, A.;Wada, A.
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Year :
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1991
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Title :
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2 Types of Linkage between Codon Usage and Gene-Expression Levels
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Journal :
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Febs Letters
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Volume :
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289
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Issue :
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1
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Pages :
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123-125
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Date :
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Sep 2
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Short Title :
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2 Types of Linkage between Codon Usage and Gene-Expression Levels
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Alternate Journal :
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FEBS Lett.
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Custom 2 :
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ISI:A1991GE52300030
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Abstract :
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The relation between codon usage and gene-expression levels is an intensively investigated and discussed topic in the field of molecular evolution. We statistically analyzed 25 Escherichia coli gene sequences by a new classification of synonymous codons and found that (i) there are two distinct types of linkage between codon usage and gene-expression levels in E. coli, and (ii) one of the two kinds of codon preferences (the codon preference concerned with interaction of GC/AT choice at three codon positions) is observed significantly in weakly expressed genes.
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Notes :
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Times Cited: 7
GE523
FEBS LETT
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| -- contributed by John Beatty, March 29, 2002 |
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