Molecular Evolution Activities
 

This is a comprehensive bibliography (under construction) of primary and secondary sources on the neutral theory of molecular evolution. It currently covers the period 1973-2001.

Author :

Phelps, F. M.

Year :

1991

Title :

Multicomponent Rank Selection as an Alternative to Haldane Dilemma

Journal :

Ima Journal of Mathematics Applied in Medicine and Biology

Volume :

8

Issue :

1

Pages :

57-72

Short Title :

Multicomponent Rank Selection as an Alternative to Haldane Dilemma

Alternate Journal :

IMA J. Math. Appl. Med. Biol.

Custom 2 :

ISI:A1991FQ20400003

Abstract :

This paper demonstrates that multicomponent hard selection (hard selection performed sequentially in n independent fitness components of the genome) is incompatible with observed substitution rates. It also shows that multicomponent rank selection permits enough differential viability to account for arbitrarily rapid evolution. This removes a major objection to the acceptance of 'rank' or 'soft' selection as a resolution of 'Haldane's dilemma' and provides firm grounds for rejecting Kimura's genetic load argument for the neutral theory.

Notes :

Times Cited: 0 FQ204 IMA J MATH APPL MED BIOL
 -- contributed by John Beatty, March 29, 2002