Molecular Evolution Activities
 

This is a comprehensive bibliography (under construction) of primary and secondary sources on the neutral theory of molecular evolution. It currently covers the period 1973-2001.

Author :

Skibinski, D. O. F.

Year :

2000

Title :

DNA tests of neutral theory: applications in marine genetics

Journal :

Hydrobiologia

Volume :

420

Pages :

137-152

Date :

Feb

Short Title :

DNA tests of neutral theory: applications in marine genetics

Alternate Journal :

Hydrobiologia

Custom 2 :

ISI:000086541700016

Abstract :

The principal methods of using DNA sequence information to test the neutral theory of evolution and polymorphism are described. These include the use of synonymous and nonsynonymous substitutions for detecting purifying and positive selection, the analysis of nucleotide diversity, mismatch analysis and the HKA, McDonald-Kreitman, Tajima and Ewens-Watterson tests. Analysis of the covariation of different kinds of molecular markers and the relationship between genetic variation and fitness is also considered. Examples of the use of these approaches in a wide variety of marine organisms are described. It is emphasised that tests of neutral theory, in addition to providing important fundamental knowledge about the action of evolutionary forces, provide valuable information about the influence of environmental and demographic factors.

Notes :

Times Cited: 1 305LN HYDROBIOLOGIA
 -- contributed by John Beatty, March 29, 2002