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A Molecular Switch for the Neuron-Glia Developmental Decision

Anderson, David J. (1995) A Molecular Switch for the Neuron-Glia Developmental Decision. Neuron, 15 (6). pp. 1219-1222. ISSN 0896-6273. doi:10.1016/0896-6273(95)90001-2.

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The genetic analysis of nervous system development has revealed a· wealth of information about the molecular mechanisms that generate neural precursors and neuronal cell type diversity (Shankland and Macagno, 1992). Until recently, however, relatively little has been known about the genetic control of gliogenesis, in part because of the comparative lack of early markers specific for glial cells or their immediate precursors' in organisms amenable to genetic analysis, such as Drosophila. One general rule that has emerged from lineage analysis of neurogenesis is that neurons and glia share a common precursor. This has been demonstrated in both the CNS and the PNS of both vertebrates and invertebrates (for reviews, see Anderson, 1989; McConnell, 1991; Doe and Technau, 1993; Jan and Jan, 1994).

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Anderson, David J.0000-0001-6175-3872
Additional Information:© 1995 by Cell Press. Under an Elsevier user license. Available online 22 October 2003.
Issue or Number:6
Record Number:CaltechAUTHORS:20150225-074536533
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Official Citation:David J. Anderson, A molecular switch for the neuron-glia developmental decision, Neuron, Volume 15, Issue 6, December 1995, Pages 1219-1222, ISSN 0896-6273, (
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:55178
Deposited By: Ruth Sustaita
Deposited On:25 Feb 2015 16:20
Last Modified:10 Nov 2021 20:42

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