Anderson, David J. (1999) Lineages and transcription factors in the specification of vertebrate primary sensory neurons. Current Opinion in Neurobiology, 9 (5). pp. 517-524. ISSN 0959-4388. doi:10.1016/S0959-4388(99)00015-X. https://resolver.caltech.edu/CaltechAUTHORS:20150226-111005840
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Abstract
Recent advances have indentified some of the key transcriptional regulators of mammalian genes, the neurogenins. Neurogenins 1 and 2 appear to control distinct sublineages for different classes of sensory neurons, including a ‘pioneer’ lineage for proprioceptors specified early in neural crest migration. Neurogenins act via a cascade of downstream transcriptional regulators, some of which have been identified.
| Item Type: | Article | ||||||||||
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| Additional Information: | © 1999 Elsevier Science Ltd. Available online 28 December 1999. Tire author thanks members of his laboratory, TM Jessell and E Frank for insightful discussions. Portions of the work from the author's laboratory were supported by grants from the March of Dimes and an NIMH Silvio Conic Center grant (Henry bester, PI). DJ Anderson is an Investigator of the Howard Hughes Medical Institute. | ||||||||||
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| Subject Keywords: | Sensory neurons; Neurogenesis; Transcription factor; Proneural gene; Neurogenin; bHLH protein | ||||||||||
| Issue or Number: | 5 | ||||||||||
| DOI: | 10.1016/S0959-4388(99)00015-X | ||||||||||
| Record Number: | CaltechAUTHORS:20150226-111005840 | ||||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20150226-111005840 | ||||||||||
| Official Citation: | David J Anderson, Lineages and transcription factors in the specification of vertebrate primary sensory neurons, Current Opinion in Neurobiology, Volume 9, Issue 5, 1 October 1999, Pages 517-524, ISSN 0959-4388, http://dx.doi.org/10.1016/S0959-4388(99)00015-X. (http://www.sciencedirect.com/science/article/pii/S095943889900015X) | ||||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||
| ID Code: | 55256 | ||||||||||
| Collection: | CaltechAUTHORS | ||||||||||
| Deposited By: | Ruth Sustaita | ||||||||||
| Deposited On: | 26 Feb 2015 19:22 | ||||||||||
| Last Modified: | 10 Nov 2021 20:43 |
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