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Cellular and molecular biology of neural crest cell lineage determination

Anderson, David J. (1997) Cellular and molecular biology of neural crest cell lineage determination. Trends in Genetics, 13 (7). pp. 276-280. ISSN 0168-9525. doi:10.1016/S0168-9525(97)01187-6.

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The past few years have seen an explosion of information about genes that control the development of the neural crest, a structure unique to vertebrate embryogenesis. Many of these genes are mutated in human diseases that affect crest-derived lineages. At the same time, decades of work on the neural crest at the cellular level are generating new insights into the segregation of different lineages and the role played by environmental signals in the lineage-commitment process. The challenge now is to integrate the cellular and molecular genetic perspectives on neural crest development. This review attempts such a synthesis.

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Anderson, David J.0000-0001-6175-3872
Additional Information:© 1997 Elsevier Science. Available online 10 December 1997. Work described from the author's laboratory was supported by the NIH, Muscular Dystrophy Association and the Howard Hughes Medical Institute. I thank members of my laboratory for helpful discussions, and Nirao Shah for the preparation of Fig.1
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Muscular Dystrophy AssociationUNSPECIFIED
Howard Hughes Medical Institute (HHMI)UNSPECIFIED
Issue or Number:7
Record Number:CaltechAUTHORS:20150226-111906850
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Official Citation:David J. Anderson, Cellular and molecular biology of neural crest cell lineage determination, Trends in Genetics, Volume 13, Issue 7, July 1997, Pages 276-280, ISSN 0168-9525, (
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:55257
Deposited By: Ruth Sustaita
Deposited On:26 Feb 2015 19:49
Last Modified:10 Nov 2021 20:43

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