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Can stem cells cross lineage boundaries?

Anderson­, David J. and Gage, Fred H. and Weissman, Irving L. (2001) Can stem cells cross lineage boundaries? Nature Medicine, 7 (4). pp. 393-395. ISSN 1078-8956. doi:10.1038/86439.

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Stem cells have traditionally been characterized as either embryonic (pluripotent) or organ-specific. Recent work suggests that the latter can "transdifferentiate" into other cell types, carrying significant implications for possible clinical use of these cells. Here the authors critically examine the existing data, and suggest standards for the evaluation of these and future studies.

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Anderson­, David J.0000-0001-6175-3872
Additional Information:© 2001 Nature Publishing Group. D.J.A. is an Investigator of the Howard Hughes Medical Institute; F.H.G. is supported by the National Institutes of Health and I.J.W. is supported by the National Institutes of Health.
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Howard Hughes Medical Institute (HHMI)UNSPECIFIED
Issue or Number:4
Record Number:CaltechAUTHORS:20150311-150256418
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Official Citation:Anderson, D. J., Gage, F. H., & Weissman, I. L. (2001). Can stem cells cross lineage boundaries? [10.1038/86439]. Nat Med, 7(4), 393-395.
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:55714
Deposited By: Joanne McCole
Deposited On:26 Mar 2015 19:55
Last Modified:10 Nov 2021 20:49

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