A Caltech Library Service

The N-end rule and regulation of apoptosis

Varshavsky, Alexander (2003) The N-end rule and regulation of apoptosis. Nature Cell Biology, 5 (5). pp. 373-376. ISSN 1465-7392. doi:10.1038/ncb0503-373.

[img] PDF - Published Version
See Usage Policy.


Use this Persistent URL to link to this item:


The ubiquitin-dependent N-end rule pathway targets proteins for degradation through their destabilizing N-terminal residues. This pathway is known to control the import of peptides, chromosome stability and cardiovascular development. A new report identifies yet another function of the N-end rule pathway: the regulation of apoptosis through degradation of Drosophila melanogaster DIAP1.

Item Type:Article
Related URLs:
URLURL TypeDescription DOIArticle ReadCube access
Varshavsky, Alexander0000-0002-4011-258X
Additional Information:© 2003 Nature Publishing Group.
Issue or Number:5
Record Number:CaltechAUTHORS:20150325-153608289
Persistent URL:
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:56090
Deposited By: Tony Diaz
Deposited On:26 Mar 2015 02:37
Last Modified:10 Nov 2021 20:54

Repository Staff Only: item control page