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Electrochemical DNA sensors

Drummond, T. Gregory and Hill, Michael G. and Barton, Jacqueline K. (2003) Electrochemical DNA sensors. Nature Biotechnology, 21 (10). pp. 1192-1199. ISSN 1087-0156. doi:10.1038/nbt873. https://resolver.caltech.edu/CaltechAUTHORS:20150325-155341855

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Abstract

Electrochemistry-based sensors offer sensitivity, selectivity and low cost for the detection of selected DNA sequences or mutated genes associated with human disease. DNA-based electrochemical sensors exploit a range of different chemistries, but all take advantage of nanoscale interactions between the target in solution, the recognition layer and a solid electrode surface. Numerous approaches to electrochemical detection have been developed, including direct electrochemistry of DNA, electrochemistry at polymer-modified electrodes, electrochemistry of DNA-specific redox reporters, electrochemical amplifications with nanoparticles, and electrochemical devices based on DNA-mediated charge transport chemistry.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1038/nbt873DOIArticle
http://www.nature.com/nbt/journal/v21/n10/full/nbt873.htmlPublisherArticle
ORCID:
AuthorORCID
Barton, Jacqueline K.0000-0001-9883-1600
Additional Information:© 2003 Nature Publishing Group. Published online 30 September 2003. We are grateful to the National Institutes of Health for their financial support of our research.
Funders:
Funding AgencyGrant Number
NIHUNSPECIFIED
Issue or Number:10
DOI:10.1038/nbt873
Record Number:CaltechAUTHORS:20150325-155341855
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20150325-155341855
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:56093
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:26 Mar 2015 02:31
Last Modified:10 Nov 2021 20:54

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