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Molecular physiology of P2X receptors and ATP signalling at synapses

Khakh, Baljit S. (2001) Molecular physiology of P2X receptors and ATP signalling at synapses. Nature Reviews Neuroscience, 2 (3). pp. 165-174. ISSN 1471-003X. doi:10.1038/35058521.

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ATP is found in every cell, where it is a major source of energy. But in the nervous system, ATP also has additional actions, which include its role in fast synaptic transmission and modulation. Here I discuss the 'fast' actions of ATP at synapses, the properties of the receptors that are activated by ATP and the physiology of ATP signalling, with emphasis on its role in pain processing.

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Additional Information:© 2001 Macmillan Magazines Ltd. While at Caltech, B.S.K. was supported by a Wellcome Trust (UK) International Prize Travelling Research Fellowship and Roche Bioscience (Palo Alto). Many thanks to Cesar Labarca for comments on the paper and to Henry A. Lester for encouragement.
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Roche BioscienceUNSPECIFIED
Issue or Number:3
Record Number:CaltechAUTHORS:20150327-150141204
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:56197
Deposited By: Tony Diaz
Deposited On:27 Mar 2015 22:07
Last Modified:10 Nov 2021 20:56

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