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Investigating T-cell memory

Mantovani, Alberto (2000) Investigating T-cell memory. Nature, 407 (6800). p. 40. ISSN 0028-0836. http://resolver.caltech.edu/CaltechAUTHORS:20150330-110250643

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Abstract

Memory is a long-recognized, crucial and poorly understood property of adaptive immunity. Jacob and Baltimore have designed an elegant genetic approach to marking memory T cells and their precursors irreversibly and have obtained intriguing results. I suggest that the particular enzyme (human placental alkaline phosphatase) chosen for irreversible marking in postnatal life contributes to certain features of this system and perturbs the homeostatic mechanisms of T-cell activation and death.


Item Type:Article
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URLURL TypeDescription
http://dx.doi.org/10.1038/35024159DOIArticle
http://www.nature.com/nature/journal/v407/n6800/abs/407040a0.htmlPublisherArticle
http://rdcu.be/cq1qPublisherFree ReadCube access
Additional Information:© 2000 Macmillan Magazines Ltd.
Record Number:CaltechAUTHORS:20150330-110250643
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20150330-110250643
Official Citation:Immunology: Investigating T-cell memory p40 Alberto Mantovani doi:10.1038/35024159
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:56214
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:30 Mar 2015 19:43
Last Modified:30 Mar 2015 19:43

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