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Integrated nanoliter systems

Hong, Jong Wook and Quake, Stephen R. (2003) Integrated nanoliter systems. Nature Biotechnology, 21 (10). pp. 1179-1183. ISSN 1087-0156. doi:10.1038/nbt871.

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Microfluidic chip platforms for manipulating liquid volumes in the nanoliter range are slowly inching their way into mainstream genomic and proteomic research. The principal challenge faced by these technologies is the need for high-throughput processing of increasingly smaller volumes, with ever higher degrees of parallelization. Significant advances have been made over the past few years in addressing these needs through electrokinetic manipulation, vesicle encapsulation and mechanical valve approaches. These strategies allow levels of integration density and platform complexity that promise to make them into serious alternatives to current robotic systems.

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Additional Information:© 2003 Nature Publishing Group. Published online: 30 September 2003. The authors would like to thank the various members of the Quake group, past and present, for many stimulating discussions.
Issue or Number:10
Record Number:CaltechAUTHORS:20150401-080430068
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:56264
Deposited By: Tony Diaz
Deposited On:01 Apr 2015 16:33
Last Modified:10 Nov 2021 20:57

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