Davis, Mark E. and Brewster, Marcus E. (2004) Cyclodextrin-based pharmaceutics: Past, present and future. Nature Reviews Drug Discovery, 3 (12). pp. 1023-1035. ISSN 1474-1776. doi:10.1038/nrd1576. https://resolver.caltech.edu/CaltechAUTHORS:20150408-151729591
Full text is not posted in this repository. Consult Related URLs below.
Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20150408-151729591
Abstract
Cyclodextrins are cyclic oligomers of glucose that can form water-soluble inclusion complexes with small molecules and portions of large compounds. These biocompatible, cyclic oligosaccharides do not elicit immune responses and have low toxicities in animals and humans. Cyclodextrins are used in pharmaceutical applications for numerous purposes, including improving the bioavailability of drugs. Current cyclodextrin-based therapeutics are described and possible future applications discussed. Cyclodextrin-containing polymers are reviewed and their use in drug delivery presented. Of specific interest is the use of cyclodextrin-containing polymers to provide unique capabilities for the delivery of nucleic acids.
Item Type: | Article | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Related URLs: |
| ||||||||||||
ORCID: |
| ||||||||||||
Additional Information: | © 2004 Nature Publishing Group. | ||||||||||||
Issue or Number: | 12 | ||||||||||||
DOI: | 10.1038/nrd1576 | ||||||||||||
Record Number: | CaltechAUTHORS:20150408-151729591 | ||||||||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20150408-151729591 | ||||||||||||
Official Citation: | Cyclodextrin-based pharmaceutics: past, present and future Mark E. Davis & Marcus E. Brewster p1023 | doi:10.1038/nrd1576 | ||||||||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||||
ID Code: | 56498 | ||||||||||||
Collection: | CaltechAUTHORS | ||||||||||||
Deposited By: | Ruth Sustaita | ||||||||||||
Deposited On: | 08 Apr 2015 22:28 | ||||||||||||
Last Modified: | 10 Nov 2021 21:00 |
Repository Staff Only: item control page