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Multiplexing using synchrony in the zebrafish olfactory bulb

Friedrich, Rainer W. and Habermann, Christopher J. and Laurent, Gilles (2004) Multiplexing using synchrony in the zebrafish olfactory bulb. Nature Neuroscience, 7 (8). pp. 862-871. ISSN 1097-6256. doi:10.1038/nn1292. https://resolver.caltech.edu/CaltechAUTHORS:20150409-085339233

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Abstract

In the olfactory bulb (OB) of zebrafish and other species, odors evoke fast oscillatory population activity and specific firing rate patterns across mitral cells (MCs). This activity evolves over a few hundred milliseconds from the onset of the odor stimulus. Action potentials of odor-specific MC subsets phase-lock to the oscillation, defining small and distributed ensembles within the MC population output. We found that oscillatory field potentials in the zebrafish OB propagate across the OB in waves. Phase-locked MC action potentials, however, were synchronized without a time lag. Firing rate patterns across MCs analyzed with low temporal resolution were informative about odor identity. When the sensitivity for phase-locked spiking was increased, activity patterns became progressively more informative about odor category. Hence, information about complementary stimulus features is conveyed simultaneously by the same population of neurons and can be retrieved selectively by biologically plausible mechanisms, indicating that seemingly alternative coding strategies operating on different time scales may coexist.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1038/nn1292DOIArticle
http://www.nature.com/neuro/journal/v7/n8/abs/nn1292.htmlPublisherArticle
http://www.nature.com/neuro/journal/v7/n8/suppinfo/nn1292_S1.htmlRelated ItemSupplementary Information
ORCID:
AuthorORCID
Laurent, Gilles0000-0002-2296-114X
Additional Information:© 2004 Nature Publishing Group. Received 22 March 2004; Accepted 11 June 2004; Published online: 25 July 2004. We thank A. Schäfer and members of the Friedrich and Laurent labs for helpful discussions and/or comments on the manuscript. This work was supported by the Max-Planck Society, the Deutsche Forschungsgemeinschaft (DFG), the National Institutes for Deafness and other Communication Disorders (NIDCD), the Keck Foundation and the McKnight Foundation.
Funders:
Funding AgencyGrant Number
Max-Planck SocietyUNSPECIFIED
Deutsche Forschungsgemeinschaft (DFG)UNSPECIFIED
National Institutes for Deafness and other Communication Disorders (NIDCD)UNSPECIFIED
W. M. Keck FoundationUNSPECIFIED
McKnight FoundationUNSPECIFIED
Issue or Number:8
DOI:10.1038/nn1292
Record Number:CaltechAUTHORS:20150409-085339233
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20150409-085339233
Official Citation:Multiplexing using synchrony in the zebrafish olfactory bulb pp862 - 871 Rainer W Friedrich, Christopher J Habermann & Gilles Laurent Published online: 25 July 2004 | doi:10.1038/nn1292
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:56508
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:09 Apr 2015 19:09
Last Modified:10 Nov 2021 21:00

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