A Caltech Library Service

Role of Environmental Signals and Transcriptional Regulators in Neural Crest Development

Groves, Andrew K. and Anderson, David J. (1996) Role of Environmental Signals and Transcriptional Regulators in Neural Crest Development. Genesis, 18 (1). pp. 64-72. ISSN 1526-954X. doi:10.1002/(SICI)1520-6408(1996)18:1<64::AID-DVG7>3.0.CO;2-#.

Full text is not posted in this repository. Consult Related URLs below.

Use this Persistent URL to link to this item:


The processes by which undifferentiated cells are assigned to particular fates are far from clear. We review recent work that has examined this problem in the neural crest, a multipotential cell population that gives rise to peripheral neurons in vertebrates. Peripheral neuronal differentiation appears to occur in a series of developmental steps that can be regulated independently by signals in the environment. Furthermore, such steps are reflected by corresponding changes in the pattern of regulatory transcription factor expression in differentiating neural crest cells. The determination of neuronal identity may proceed by a series of parallel regulatory pathways involving transcription factors acting both in cascades and in combinatorial arrays.

Item Type:Article
Related URLs:
URLURL TypeDescription<64::AID-DVG7>3.0.CO;2-#DOIArticle
Anderson, David J.0000-0001-6175-3872
Additional Information:© 1996 Wiley-Liss, Inc. Received for publication May 21, 1995; accepted June 15, 1995.
Subject Keywords:Neural crest; neuronal identity; transcription factors
Issue or Number:1
Record Number:CaltechAUTHORS:20150416-094501867
Persistent URL:
Official Citation:Groves, A. K. and Anderson, D. J. (1996), Role of environmental signals and transcriptional regulators in neural crest development. Dev. Genet., 18: 64–72. doi: 10.1002/(SICI)1520-6408(1996)18:1<64::AID-DVG7>3.0.CO;2-#
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:56716
Deposited By: Jason Perez
Deposited On:16 Apr 2015 16:59
Last Modified:10 Nov 2021 21:02

Repository Staff Only: item control page