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The determination of the neuronal phenotype

Anderson, David J. and Jan, Yuh Nung (1997) The determination of the neuronal phenotype. In: Molecular and Cellular Approaches to Neural Development. Oxford University Press , New York, NY, pp. 26-63. ISBN 9780195111668.

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This chapter addresses the following questions: What are the key regulatory genes that specify a neuronal fate and a particular neuronal identity? What do they do? How are they controlled? In addition of identifying key regulatory genes, an attempt is also made to address the “logic” of neuronal determination and differentiation. It argues that current knowledge of the details of the underlying molecular genetic circuitry that determines the identity of any kind of neuron, in any organism, remains sketchy. However, a few general principles are beginning to emerge, particularly the idea that neuronal identity is implemented in series and in parallel in a collection of subprograms, rather than one coordinately active “master” program.

Item Type:Book Section
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Anderson, David J.0000-0001-6175-3872
Additional Information:© 1997 Oxford University Press.
Subject Keywords:Drosophila, neuronal determination, neuronal differentiation, regulatroy genes, subprograms
Record Number:CaltechAUTHORS:20150416-094607162
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:56717
Deposited By: Tony Diaz
Deposited On:16 Apr 2015 16:55
Last Modified:10 Nov 2021 21:02

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