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Gene Expression and the Diversity of Identified Neurons

Buck, L. and Stein, R. and Palazzolo, M. and Anderson, D. J. and Axel, R. (1983) Gene Expression and the Diversity of Identified Neurons. Cold Spring Harbor Symposia on Quantitative Biology, 48 . pp. 485-492. ISSN 0091-7451. doi:10.1101/SQB.1983.048.01.053.

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Nervous systems consist of diverse populations of neurons that are anatomically and functionally distinct. The diversity of neurons and the precision with which they are interconnected suggest that specific genes or sets of genes are activated in some neurons but not expressed in others. Experimentally, this problem may be considered at two levels. First, what is the total number of genes expressed in the brain, and how are they distributed among the different populations of neurons? Second, can we identify specific genes expressed in individual neurons and relate the expression of these genes to the unique functional properties of these neurons?

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Anderson, D. J.0000-0001-6175-3872
Additional Information:© 1983 Cold Spring Harbor Laboratory Press. The Authors acknowledge that six months after the full-issue publication date, the Article will be distributed under a Creative Commons CC-BY-NC License (Attribution-NonCommercial 4.0 International License, This work was supported by a grant from the National Institutes of Health to R.A. and by fellowships from the Cancer Research Institute, Inc., to L.B., from the National Institutes of Health to R.S., and from the Helen Hay Whitney Foundation to D.A.
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Cancer Research InstituteUNSPECIFIED
Helen Hay Whitney FoundationUNSPECIFIED
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Official Citation:Gene Expression and the Diversity of Identified Neurons L. Buck, R. Stein, M. Palazzolo, D.J. Anderson, and R. Axel Cold Spring Harb Symp Quant Biol 1983 48: 485-492; doi:10.1101/SQB.1983.048.01.053
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:56838
Deposited On:21 Apr 2015 22:21
Last Modified:10 Nov 2021 21:04

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