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Nuclear magnetic resonance studies of ^(13)CO monoxide binding to various hemoglobins

Moon, Richard B. and Richards, John H. (1972) Nuclear magnetic resonance studies of ^(13)CO monoxide binding to various hemoglobins. Journal of the American Chemical Society, 94 (14). pp. 5093-5095. ISSN 0002-7863. doi:10.1021/ja00769a058.

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Whether, and to what extent, the various subunits of hemoglobin interact differently with ligands (such as oxygen or carbon monoxide) remains one of the unanswered questions in the hemoglobin saga. These possible differences may manifest themselves in the kinetic or thermodynamic affinities for ligands or in the environments experienced by ligands when bound to various subunits.

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Additional Information:© 1972 American Chemical Society. Received April 21, 1972. We wish to thank K. Dill for providing myoglobin samples and Dr. D. Powars of the Los Angeles County-USC Medical Center for providing samples of fetal blood.
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Caltech Gates and Crellin Laboratories of Chemistry4449
Issue or Number:14
Record Number:CaltechAUTHORS:20150505-130344245
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Official Citation:Nuclear magnetic resonance studies of carbon-13 monoxide binding to various hemoglobins Richard B. Moon and John H. Richards Journal of the American Chemical Society 1972 94 (14), 5093-5095 DOI: 10.1021/ja00769a058
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:57237
Deposited By: Tony Diaz
Deposited On:06 May 2015 16:40
Last Modified:10 Nov 2021 21:10

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