Richards, John H. (1963) Role of Acetate in Biosynthesis. Antimicrobial Agents and Chemotherapy, 161 . pp. 349-351. ISSN 0066-4804. https://resolver.caltech.edu/CaltechAUTHORS:20150506-092654869
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Abstract
The role of acetate in the biosynthesis of a large number of antibiotics and other natural products is discussed. Included are simple substances apparently derived from acetate by molecular rearrangements, such as patulin and the fungal tropolone acids, puberlonic and stipitatic acids. The origin of more complex antibiotics such as oxytetracycline is considered, as well as the genesis of depsidones (such as nidulin) from lichens and fungi. The involvement of acetate in the biosynthesis of various classes of alkaloids, such as the indoles, strychnine, and ajmaline, is also discussed. More recent developments in the biochemical details of these processes, such as the role of malonate, is particularly stressed.
Item Type: | Article | ||||
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Additional Information: | © 1963 American Society for Microbiology. | ||||
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Record Number: | CaltechAUTHORS:20150506-092654869 | ||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20150506-092654869 | ||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||
ID Code: | 57258 | ||||
Collection: | CaltechAUTHORS | ||||
Deposited By: | Tony Diaz | ||||
Deposited On: | 06 May 2015 17:09 | ||||
Last Modified: | 03 Oct 2019 08:22 |
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