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Chemical approaches to deciphering the glycosaminoglycan code

Gama, Cristal I. and Hsieh-Wilson, Linda C. (2005) Chemical approaches to deciphering the glycosaminoglycan code. Current Opinion in Chemical Biology, 9 (6). pp. 609-619. ISSN 1367-5931. doi:10.1016/j.cbpa.2005.10.003.

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Glycosaminoglycans are sulfated biopolymers with rich chemical diversity and complex functions in vivo, contributing to processes ranging from cell growth and neuronal development to viral invasion and neurodegenerative disease. Recent studies suggest that glycosaminoglycans may encode information in the form of a ‘sulfation code,’ whereby discrete modifications to the polysaccharide backbone may direct the location or activities of proteins.

Item Type:Article
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URLURL TypeDescription DOIArticle
Hsieh-Wilson, Linda C.0000-0001-5661-1714
Additional Information:© 2005 Elsevier Ltd. Available online 18th October 2005. We thank the Hsieh-Wilson laboratory for helpful discussions. This research was supported by the Human Frontiers Science Program (RGY0072), National Institutes of Health (RO1 NS045061) and Alfred P. Sloan Foundation.
Funding AgencyGrant Number
Human Frontier Science ProgramRGY0072
NIHRO1 NS045061
Alfred P. Sloan FoundationUNSPECIFIED
Issue or Number:6
Record Number:CaltechAUTHORS:20150519-091840382
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Official Citation:Cristal I Gama, Linda C Hsieh-Wilson, Chemical approaches to deciphering the glycosaminoglycan code, Current Opinion in Chemical Biology, Volume 9, Issue 6, December 2005, Pages 609-619, ISSN 1367-5931, (
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:57639
Deposited By: Tony Diaz
Deposited On:19 May 2015 16:50
Last Modified:10 Nov 2021 21:53

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