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Extending the recognition site of designed minor groove binding molecules

Geierstanger, Bernhard H. and Mrksich, Milan and Dervan, Peter B. and Wemmer, David E. (1996) Extending the recognition site of designed minor groove binding molecules. Nature Structural Biology, 3 (4). pp. 321-324. ISSN 1072-8368. doi:10.1038/nsb0496-321.

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A linked, imazole/pyrrole minor-groove ligand has been shown to bind sequence specificially to a 13 base-pair target sequence in a mixed 1:1/2:1 mode.

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Dervan, Peter B.0000-0001-8852-7306
Additional Information:© 1996 Nature Publishing Group. Received 28 August 1995; Accepted 22 February 1996. B.H.G. and D.E.W. thank H.P. Spielmann, P.A. Fagan, T.D. Cole and R. Pelaez for helpful discussions. We are grateful to National Institutes of Health and the National Foundation for Cancer Research for research support, to the Ralph M. Parson Foundation for a graduate fellowship to M.M., and to the U.S. Department of Energy and National Science Foundation for instrumentation grants.
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National Foundation for Cancer ResearchUNSPECIFIED
Ralph M. Parsons FoundationUNSPECIFIED
Department of Energy (DOE)UNSPECIFIED
Issue or Number:4
Record Number:CaltechAUTHORS:20150624-144700360
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Official Citation:Geierstanger, B. H., Mrksich, M., Dervan, P. B., & Wemmer, D. E. (1996). Extending the recognition site of designed minor groove binding molecules. [10.1038/nsb0496-321]. Nat Struct Mol Biol, 3(4), 321-324.
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ID Code:58590
Deposited On:24 Jun 2015 22:05
Last Modified:10 Nov 2021 22:07

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