Extending the recognition site of designed minor groove binding molecules

Geierstanger, Bernhard H. and Mrksich, Milan and Dervan, Peter B. and Wemmer, David E. (1996) Extending the recognition site of designed minor groove binding molecules. Nature Structural Biology, 3 (4). pp. 321-324. ISSN 1072-8368. doi:10.1038/nsb0496-321. https://resolver.caltech.edu/CaltechAUTHORS:20150624-144700360

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Abstract

A linked, imazole/pyrrole minor-groove ligand has been shown to bind sequence specificially to a 13 base-pair target sequence in a mixed 1:1/2:1 mode.

Item Type:

Article

Related URLs:

URL	URL Type	Description
http://dx.doi.org/10.1038/nsb0496-321	DOI	Article
http://www.nature.com/nsmb/journal/v3/n4/abs/nsb0496-321.html	Publisher	Article

ORCID:

Author	ORCID
Dervan, Peter B.	0000-0001-8852-7306

Additional Information:

© 1996 Nature Publishing Group. Received 28 August 1995; Accepted 22 February 1996. B.H.G. and D.E.W. thank H.P. Spielmann, P.A. Fagan, T.D. Cole and R. Pelaez for helpful discussions. We are grateful to National Institutes of Health and the National Foundation for Cancer Research for research support, to the Ralph M. Parson Foundation for a graduate fellowship to M.M., and to the U.S. Department of Energy and National Science Foundation for instrumentation grants.

Funders:

Funding Agency	Grant Number
NIH	UNSPECIFIED
National Foundation for Cancer Research	UNSPECIFIED
Ralph M. Parsons Foundation	UNSPECIFIED
Department of Energy (DOE)	UNSPECIFIED
NSF	UNSPECIFIED

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DOI:

10.1038/nsb0496-321

Record Number:

CaltechAUTHORS:20150624-144700360

Persistent URL:

https://resolver.caltech.edu/CaltechAUTHORS:20150624-144700360

Official Citation:

Geierstanger, B. H., Mrksich, M., Dervan, P. B., & Wemmer, D. E. (1996). Extending the recognition site of designed minor groove binding molecules. [10.1038/nsb0496-321]. Nat Struct Mol Biol, 3(4), 321-324.

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58590

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CaltechAUTHORS

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Deposited On:

24 Jun 2015 22:05

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10 Nov 2021 22:07

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