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Extending the recognition site of designed minor groove binding molecules

Geierstanger, Bernhard H. and Mrksich, Milan and Dervan, Peter B. and Wemmer, David E. (1996) Extending the recognition site of designed minor groove binding molecules. Nature Structural Biology, 3 (4). pp. 321-324. ISSN 1072-8368. doi:10.1038/nsb0496-321. https://resolver.caltech.edu/CaltechAUTHORS:20150624-144700360

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Abstract

A linked, imazole/pyrrole minor-groove ligand has been shown to bind sequence specificially to a 13 base-pair target sequence in a mixed 1:1/2:1 mode.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1038/nsb0496-321DOIArticle
http://www.nature.com/nsmb/journal/v3/n4/abs/nsb0496-321.htmlPublisherArticle
ORCID:
AuthorORCID
Dervan, Peter B.0000-0001-8852-7306
Additional Information:© 1996 Nature Publishing Group. Received 28 August 1995; Accepted 22 February 1996. B.H.G. and D.E.W. thank H.P. Spielmann, P.A. Fagan, T.D. Cole and R. Pelaez for helpful discussions. We are grateful to National Institutes of Health and the National Foundation for Cancer Research for research support, to the Ralph M. Parson Foundation for a graduate fellowship to M.M., and to the U.S. Department of Energy and National Science Foundation for instrumentation grants.
Funders:
Funding AgencyGrant Number
NIHUNSPECIFIED
National Foundation for Cancer ResearchUNSPECIFIED
Ralph M. Parsons FoundationUNSPECIFIED
Department of Energy (DOE)UNSPECIFIED
NSFUNSPECIFIED
Issue or Number:4
DOI:10.1038/nsb0496-321
Record Number:CaltechAUTHORS:20150624-144700360
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20150624-144700360
Official Citation:Geierstanger, B. H., Mrksich, M., Dervan, P. B., & Wemmer, D. E. (1996). Extending the recognition site of designed minor groove binding molecules. [10.1038/nsb0496-321]. Nat Struct Mol Biol, 3(4), 321-324.
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:58590
Collection:CaltechAUTHORS
Deposited By: Joanne McCole
Deposited On:24 Jun 2015 22:05
Last Modified:10 Nov 2021 22:07

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