Kasamatsu, Takuji and Pettigrew, John D. (1976) Depletion of brain catecholamines: failure of ocular dominance shift after monocular occlusion in kittens. Science, 194 (4261). pp. 206-209. ISSN 0036-8075. doi:10.1126/science.959850. https://resolver.caltech.edu/CaltechAUTHORS:20150630-160750039
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Abstract
Monocularly deprived kittens were compared with littermates that had had their eyelids sutured for the same time but that had, in addition, been treated with 6-hydroxydopamine to deplete their forebrains of catecholamines. The visual cortices of all the catecholamine-depleted kittens showed high proportions of binocular neurons, in contrast to the control group, most of whose visual cortical neurons were driven exclusively by the nondeprived eye. Catecholamines may play an important role in the maintenance of cortical plasticity during the critical period.
Item Type: | Article | ||||||||||||
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Additional Information: | © 1976 American Association for the Advancement of Science. Received 1 March 1976; Revised 7 June 1976. Supported by NIMH grant MH25852 and by the Spencer Foundation. We thank Lederle Laboratories for providing us with Flaxedil. | ||||||||||||
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Issue or Number: | 4261 | ||||||||||||
DOI: | 10.1126/science.959850 | ||||||||||||
Record Number: | CaltechAUTHORS:20150630-160750039 | ||||||||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20150630-160750039 | ||||||||||||
Official Citation: | Kasamatsu, T., & Pettigrew, J. (1976). Depletion of brain catecholamines: failure of ocular dominance shift after monocular occlusion in kittens. Science, 194(4261), 206-209. doi: 10.1126/science.959850 | ||||||||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||||
ID Code: | 58716 | ||||||||||||
Collection: | CaltechAUTHORS | ||||||||||||
Deposited By: | INVALID USER | ||||||||||||
Deposited On: | 01 Jul 2015 15:03 | ||||||||||||
Last Modified: | 10 Nov 2021 22:09 |
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