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Enantioselective and Enantiospecific Transition-Metal-Catalyzed Cross-Coupling Reactions of Organometallic Reagents To Construct C–C Bonds

Cherney, Alan H. and Kadunce, Nathaniel T. and Reisman, Sarah E. (2015) Enantioselective and Enantiospecific Transition-Metal-Catalyzed Cross-Coupling Reactions of Organometallic Reagents To Construct C–C Bonds. Chemical Reviews, 115 (17). pp. 9587-9652. ISSN 0009-2665. PMCID PMC4566132. doi:10.1021/acs.chemrev.5b00162. https://resolver.caltech.edu/CaltechAUTHORS:20150819-143512446

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Abstract

The stereocontrolled construction of C−C bonds remains one of the foremost challenges in organic synthesis. At the heart of any chemical synthesis of a natural product or designed small molecule is the need to orchestrate a series of chemical reactions to prepare and functionalize a carbon framework. The advent of transition-metal catalysis has provided chemists with a broad range of new tools to forge C−C bonds and has resulted in a paradigm shift in synthetic strategy planning. The impact of these methods was recognized with the awarding of the 2010 Nobel Prize in Chemistry to Richard Heck, Ei-ichi Negishi, and Akira Suzuki for their seminal contributions to the development of Pd-catalyzed cross-coupling.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1021/acs.chemrev.5b00162DOIArticle
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566132/PubMed CentralArticle
ORCID:
AuthorORCID
Cherney, Alan H.0000-0001-7440-6634
Kadunce, Nathaniel T.0000-0002-6566-9851
Reisman, Sarah E.0000-0001-8244-9300
Additional Information:© 2015 American Chemical Society. This is an open access article published under an ACS AuthorChoice License, which permits copying and redistribution of the article or any adaptations for non-commercial purposes. Received: March 17, 2015; Publication Date (Web): August 13, 2015. We are grateful for financial support from the National Institutes of Health (Grant GM111805-01), Novartis, and Eli Lilly. Fellowship support from Bristol-Myers Squibb (A.H.C.), the American Chemical Society Division of Organic Chemistry, with sponsorship by Amgen (A.H.C.), and the National Science Foundation (A.H.C., Grant No. DGE-1144469) is gratefully acknowledged.
Funders:
Funding AgencyGrant Number
NIHGM111805-01
NovartisUNSPECIFIED
Eli LillyUNSPECIFIED
Bristol-Myers SquibbUNSPECIFIED
American Chemical SocietyUNSPECIFIED
AmgenUNSPECIFIED
NSFDGE-1144469
Issue or Number:17
PubMed Central ID:PMC4566132
DOI:10.1021/acs.chemrev.5b00162
Record Number:CaltechAUTHORS:20150819-143512446
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20150819-143512446
Official Citation:Enantioselective and Enantiospecific Transition-Metal-Catalyzed Cross-Coupling Reactions of Organometallic Reagents To Construct C–C Bonds Alan H. Cherney, Nathaniel T. Kadunce, and Sarah E. Reisman Chemical Reviews 2015 115 (17), 9587-9652 DOI: 10.1021/acs.chemrev.5b00162
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:59772
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:19 Aug 2015 21:49
Last Modified:24 May 2022 22:36

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