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Methods for diversifying protein structure

Tirrell, David A. (2015) Methods for diversifying protein structure. In: 250th American Chemical Society National Meeting & Exposition, August 16-20, 2015, Boston, MA.

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By designing and expressing artificial genes, polymer chemists can prep. macromol. systems characterized by uniform chain length, sequence and stereochem. But the same mol. mechanisms that provide good control of chain architecture also limit the diversity of protein structure. This lecture will examine several complementary strategies for diversifying the products of cellular protein synthesis, including the incorporation of non-canonical amino acids, the prepn. of non-linear proteins, and programmed posttranslational modification.

Item Type:Conference or Workshop Item (Paper)
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Tirrell, David A.0000-0003-3175-4596
Additional Information:© 2015 American Chemical Society.
Record Number:CaltechAUTHORS:20150902-104957229
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:60030
Deposited By: Tony Diaz
Deposited On:11 Sep 2015 18:33
Last Modified:03 Oct 2019 08:52

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