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^(15)N NMR studies of biological systems

Kanamori, Keiko and Roberts, John D. (1983) ^(15)N NMR studies of biological systems. Accounts of Chemical Research, 16 (2). pp. 35-41. ISSN 0001-4842. doi:10.1021/ar00086a001.

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Nitrogen is widely distributed in biological systems and is often directly involved in biochemical processes of interest. Nitrogen-15 nuclear magnetic resonance (^(15)N NMR) spectroscopy is, therefore, potentially a very valuable technique for the study of biological systems. Within the last several years, a number of exciting, pioneering ^(15)N NMR studies of biomolecules have been reported, and this review will describe several of these in three areas of biochemistry: (1) proteins including proteolytic enzymes and hemoproteins, (2) nucleic acids and nucleotide bases and their interactions in base pairing and drug binding, and (3) in vivo metabolism and cellular dynamics in intact microorganisms and plants.

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Alternate Title:Nitrogen-15 NMR studies of biological systems
Additional Information:© 1983 American Chemical Society. Received April 15, 1982 Revised Manuscript Received September 13, 1982. Publication Date: February 1983. We are pleased to acknowledge support by the National Science Foundation and by the Public Health Service, Grant No. GM-11072 from the Division of General Medical Sciences.
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U.S. Public Health Service (USPHS)GM-11072
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Caltech Gates and Crellin Laboratories of Chemistry6635
Issue or Number:2
Record Number:CaltechAUTHORS:20151005-090621006
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Official Citation:Nitrogen-15 NMR studies of biological systems Keiko Kanamori and John D. Roberts Accounts of Chemical Research 1983 16 (2), 35-41 DOI: 10.1021/ar00086a001
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:60752
Deposited On:05 Oct 2015 16:25
Last Modified:10 Nov 2021 22:38

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