Windsor, Emanuel (1951) α-Aminoadipic acid as a precursor to lysine in Neurospora. Journal of Biological Chemistry, 192 (2). pp. 607-609. ISSN 0021-9258. https://resolver.caltech.edu/CaltechAUTHORS:WINjbc51a
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Abstract
In a recent investigation reported by Mitchell and Houlahan (1) it was shown that a mutant strain of Neurospora crassa, strain 33933, was able to utilize α-aminoadipic acid in place of lysine. Although these authors interpreted their results as showing that oc-aminoadipic acid was a precursor in the biosynthesis of lysine by Neurospora, other pathways are conceivable. During the isolation of α-aminoadipic acid from a natural protein radioactive α-aminoadipic acid was added as a marker for chromatographic analysis (2). In order to identify the isolated amino acid an aliquot was provided as a growth substance for the Neurospora mutant 33933. Thus the opportunity was available to follow the radioactivity and determine whether or not α-aminoadipic acid was a precursor to lysine.
Item Type: | Article | ||||||
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Additional Information: | Copyright © 1951 by the American Society for Biochemistry and Molecular Biology. (Received for publication, May 22, 1951) Part of this work was taken from a thesis in partial fulfilment of the requirements for the degree of Doctor of Philosophy. | ||||||
Issue or Number: | 2 | ||||||
Record Number: | CaltechAUTHORS:WINjbc51a | ||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:WINjbc51a | ||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||
ID Code: | 6204 | ||||||
Collection: | CaltechAUTHORS | ||||||
Deposited By: | Archive Administrator | ||||||
Deposited On: | 28 Nov 2006 | ||||||
Last Modified: | 02 Oct 2019 23:30 |
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