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Tolerance to Sound Intensity of Binaural Coincidence Detection in the Nucleus Laminaris of the Owl

Peña, José Luis and Viete, Svenja and Albeck, Yehuda and Konishi, Masakazu (1996) Tolerance to Sound Intensity of Binaural Coincidence Detection in the Nucleus Laminaris of the Owl. Journal of Neuroscience, 16 (21). pp. 7046-7054. ISSN 0270-6474. PMCID PMC6579264. https://resolver.caltech.edu/CaltechAUTHORS:20151201-094746964

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Abstract

Neurons of the owl's nucleus laminaris serve as coincidence detectors for measurement of interaural time difference. The discharge rate of nucleus laminaris neurons for both monaural and binaural stimulation increased with sound intensity until they reached an asymptote. Intense sounds affected neither the ratio between binaural and monaural responses nor the interaural time difference for which nucleus laminaris neurons were selective. Theoretical analysis showed that high afferent discharge rates cause coincidence detectors with only excitatory input to lose their selectivity for interaural time difference when coincidence of impulses from the same side becomes as likely as that of impulses from the two sides. We hypothesize that inhibitory input whose strength increases with sound intensity protects nucleus laminaris neurons from losing their sensitivity to interaural time difference with intense sounds.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1523/JNEUROSCI.16-21-07046.1996DOIArticle
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579264PubMed CentralArticle
Additional Information:© 1996 Society for Neuroscience. For the first six months after publication SfN’s license will be exclusive. Beginning six months after publication the Work will be made freely available to the public on SfN’s website to copy, distribute, or display under a Creative Commons Attribution 4.0 International (CC BY 4.0) license (https://creativecommons.org/licenses/by/4.0/). Received June 10, 1996; revised Aug. 7, 1996; accepted Aug. 9, 1996. This work was supported by National Institute of Neurological Disorders and Stroke Grant DC-00134 and postdoctoral fellowships from the Pew Latin American Fellows Program (J.L.P.), the Deutsche Forschungsgemeinschaft (S.V.), and the Sloan Center for Theoretical Neurobiology at Caltech (Y.A.). We thank Jamie Mazer and Chris Malek for assistance with computer programming and Catherine Carr, Roian Egnor, Jamie Mazer, Terry Takahashi, Larry Proctor, and Marc Schmidt for reading an early version of this paper. Ben Arthur commented on this manuscript.
Funders:
Funding AgencyGrant Number
NIHDC-00134
Deutsche Forschungsgemeinschaft (DFG)UNSPECIFIED
Caltech Sloan Center for Theoretical NeurobiologyUNSPECIFIED
Pew Latin American Fellows ProgramUNSPECIFIED
National Institute of Neurological Disorders and Stroke (NINDS)UNSPECIFIED
Subject Keywords:acoustic localization; interaural time difference; sound intensity; coincidence detection; nucleus laminaris; owl
Issue or Number:21
PubMed Central ID:PMC6579264
Record Number:CaltechAUTHORS:20151201-094746964
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20151201-094746964
Official Citation:Tolerance to Sound Intensity of Binaural Coincidence Detection in the Nucleus Laminaris of the Owl. Jose Luis Peña, Svenja Viete, Yehuda Albeck, Masakazu Konishi. Journal of Neuroscience 1 November 1996, 16 (21) 7046-7054; DOI: 10.1523/JNEUROSCI.16-21-07046.1996
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:62491
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:01 Dec 2015 18:24
Last Modified:04 Nov 2019 18:01

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