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Polyoma Virus: Production in Bacillus subtilis

Bayreuther, K. E. and Romig, W. R. (1964) Polyoma Virus: Production in Bacillus subtilis. Science, 146 (3645). pp. 778-779. ISSN 0036-8075. doi:10.1126/science.146.3645.778.

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Particles of complete polyoma virus are produced in competent Bacillus subtilis incubated with DNA isolated from purified, conventionally grown polyoma virus. The virus grown in B. subtilis is biologically identical to polyoma virus produced by animal cells. Quantitative parameters of the system have been established, and fluctuation tests indicate that viral replication occurs within the infected bacteria.

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Additional Information:© 1964 American Association for the Advancement of Science. Received 4 August 1964. Work supported by American Cancer Society grant No. E-193 and the James G. Boswell Foundation fund for Virus Research to K.E.B. and by Office of Naval Research grant Nonr-233(67) and Cancer Research Funds of the University of California to W.R.R. We thank G; Attardi, M. Delbrück, J. Weigle, and J. Vinograd for advice and materials; Mrs. A. Drew and Mrs. H. Eberle for assistance during the experimental work.
Funding AgencyGrant Number
American Cancer SocietyE-193
James G. Boswell FoundationUNSPECIFIED
Office of Naval Research (ONR)Nonr-233(67)
University of CaliforniaUNSPECIFIED
Issue or Number:3645
Record Number:CaltechAUTHORS:20151208-125405131
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Official Citation:Polyoma Virus: Production in Bacillus subtilis K. E. Bayreuther and W. R. Romig Science 6 November 1964: 146 (3645), 778-779. [DOI:10.1126/science.146.3645.778]
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:62708
Deposited By: Tony Diaz
Deposited On:08 Dec 2015 22:26
Last Modified:10 Nov 2021 23:05

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