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N-Methylmetanephrine: Excretion by Juvenile Psychotics

Perry, Thomas L. (1963) N-Methylmetanephrine: Excretion by Juvenile Psychotics. Science, 139 (3555). pp. 587-589. ISSN 0036-8075. doi:10.1126/science.139.3555.587.

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Three out of 18 psychotic children excreted N-methylmetanephrine, a metabolite of N-methylepinephrine. It is not clear whether this tertiary amine plays a part in causing some forms of psychosis or is merely a secondary result of mental dysfunction. Urinary excretion of bufotenin and of 3,4-dimethoxyphenylethylamine, each of which has been reported elevated in some adult schizophrenics, was not unusual in these children.

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Additional Information:© 1963 American Association for the Advancement of Science. 7 December 1962. Contribution No. 2903, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena. I thank Dr. Julius Axelrod of the National Institutes of Health for the N-methylmetanephrine, and Dr. Robert Simonds and Dr. Percy Minden of Los Angeles for help with three of the patients studied. Supported by grants from the Richard W. Lippman Memorial Fund and the National Institutes of Health.
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Richard W. Lippman Memorial FundUNSPECIFIED
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Other Numbering System NameOther Numbering System ID
Caltech Division of Chemistry and Chemical Engineering2903
Issue or Number:3555
Record Number:CaltechAUTHORS:20151209-125440232
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Official Citation:N-Methylmetanephrine: Excretion by Juvenile Psychotics Thomas L. Perry Science 15 February 1963: 587-589.
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:62746
Deposited By: Ruth Sustaita
Deposited On:09 Dec 2015 23:22
Last Modified:10 Nov 2021 23:06

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