Perry, Thomas L. (1962) Urinary Excretion of Amines in Phenylketonuria and Mongolism. Science, 136 (3519). pp. 879-880. ISSN 0036-8075. doi:10.1126/science.136.3519.879. https://resolver.caltech.edu/CaltechAUTHORS:20151209-151747340
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Abstract
Children with phenylketonuria excrete considerably less serotonin and tryptamine and somewhat less normetanephrine and p-tyramine than normal children. The excretion of these amines was not decreased in mongolism. Even during monoamine oxidase blockade, o-tyramine could not be detected in the urine of phenylketonurics. These findings are discussed in relation to the mental defect of phenylketonuria.
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| Additional Information: | © 1962 American Association for the Advancement of Science. 22 December 1961. I am grateful to Dr. Dorothy Redlich for valuable assistance, and to Dr. Kenneth N. F. Shaw for helpful advice. This research was supported by grants from the Ford Foundation and from the National Institutes of Health. This report is contribution No. 2794 of California Institute of Technology, Pasadena. | ||||||||||||
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| Issue or Number: | 3519 | ||||||||||||
| DOI: | 10.1126/science.136.3519.879 | ||||||||||||
| Record Number: | CaltechAUTHORS:20151209-151747340 | ||||||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20151209-151747340 | ||||||||||||
| Official Citation: | Urinary Excretion of Amines in Phenylketonuria and Mongolism Thomas L. Perry Science 8 June 1962: 879-880. | ||||||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||||
| ID Code: | 62756 | ||||||||||||
| Collection: | CaltechAUTHORS | ||||||||||||
| Deposited By: | Ruth Sustaita | ||||||||||||
| Deposited On: | 10 Dec 2015 20:59 | ||||||||||||
| Last Modified: | 10 Nov 2021 23:06 |
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