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Process of Infection with φX174: Effect of Exonucleases on the Replicative Form

Burton, Alice and Sinsheimer, Robert L. (1963) Process of Infection with φX174: Effect of Exonucleases on the Replicative Form. Science, 142 (3594). pp. 962-963. ISSN 0036-8075. doi:10.1126/science.142.3594.962.

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When a preparation containing the DNA of the bacteriophage φX174 in its replicative form together with DNA from Escherichia coli is treated with exonucleases, the replicative form retains its characteristic physical properties, while the bacterial DNA is degraded. The evidence suggests that the mature replicative form exists as a closed ring.

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Additional Information:© 1963 American Association for the Advancement of Science. 26 August 1963. We thank Dr. C. C. Richardson and Dr. I. R. Lehman for generous gifts of the E. coli exonuclease III and the E. coli exonuclease I. One of us (A.B.) has been a postdoctoral fellow of the U.S. Public Health Service. This research has been supported in part by grant RG-6965 from the U.S. Public Health Service.
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U.S. Public Health Service (USPHS)RG-6965
Issue or Number:3594
Record Number:CaltechAUTHORS:20151211-083051907
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Official Citation:Process of Infection with øX174: Effect of Exonucleases on the Replicative Form Alice Burton and Robert L. Sinsheimer Science 15 November 1963: 142 (3594), 962-963. [DOI:10.1126/science.142.3594.962]
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:62786
Deposited By: Ruth Sustaita
Deposited On:11 Dec 2015 20:30
Last Modified:10 Nov 2021 23:06

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