Fenichel, I. Robert and Horowitz, Samuel B. and Cherkin, Arthur and Catchpool, J. F. (1966) Measurement of Anesthetic Potency. Science, 152 (3725). pp. 1110-1111. ISSN 0036-8075. http://resolver.caltech.edu/CaltechAUTHORS:20151214-071458387
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Abstract
In "Temperature dependence of anesthesia in goldfish" (l), Cherkin and Catchpool introduce a technique for making quantitative measurements of the anesthetic potency of water-soluble agents. Goldfish are kept swimming by an applied stimulus (an electric shock); anesthetic potency is measured as AD_(50) the dose at which 50 percent of the experimental animals fail to respond to the stimulus.
| Item Type: | Article | ||||||||||||
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| Additional Information: | © 1966 American Association for the Advancement of Science. 27 October 1965. Supported in part by NSF grant GB 3109 and PHS grant GM 11070. | ||||||||||||
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| Record Number: | CaltechAUTHORS:20151214-071458387 | ||||||||||||
| Persistent URL: | http://resolver.caltech.edu/CaltechAUTHORS:20151214-071458387 | ||||||||||||
| Official Citation: | Measurement of Anesthetic Potency I. Robert Fenichel, Samuel B. Horowitz, Arthur Cherkin, and J. F. Catchpool Science 20 May 1966: 152 (3725), 1110-1111. [DOI:10.1126/science.152.3725.1110] | ||||||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||||
| ID Code: | 62833 | ||||||||||||
| Collection: | CaltechAUTHORS | ||||||||||||
| Deposited By: | Ruth Sustaita | ||||||||||||
| Deposited On: | 14 Dec 2015 17:42 | ||||||||||||
| Last Modified: | 14 Dec 2015 17:42 |
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