Fenichel, I. Robert and Horowitz, Samuel B. and Cherkin, Arthur and Catchpool, J. F. (1966) Measurement of Anesthetic Potency. Science, 152 (3725). pp. 1110-1111. ISSN 0036-8075. doi:10.1126/science.152.3725.1110. https://resolver.caltech.edu/CaltechAUTHORS:20151214-071458387
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Abstract
In "Temperature dependence of anesthesia in goldfish" (l), Cherkin and Catchpool introduce a technique for making quantitative measurements of the anesthetic potency of water-soluble agents. Goldfish are kept swimming by an applied stimulus (an electric shock); anesthetic potency is measured as AD_(50) the dose at which 50 percent of the experimental animals fail to respond to the stimulus.
Item Type: | Article | ||||||||||||
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Additional Information: | © 1966 American Association for the Advancement of Science. 27 October 1965. Supported in part by NSF grant GB 3109 and PHS grant GM 11070. | ||||||||||||
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Issue or Number: | 3725 | ||||||||||||
DOI: | 10.1126/science.152.3725.1110 | ||||||||||||
Record Number: | CaltechAUTHORS:20151214-071458387 | ||||||||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20151214-071458387 | ||||||||||||
Official Citation: | Measurement of Anesthetic Potency I. Robert Fenichel, Samuel B. Horowitz, Arthur Cherkin, and J. F. Catchpool Science 20 May 1966: 152 (3725), 1110-1111. [DOI:10.1126/science.152.3725.1110] | ||||||||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||||
ID Code: | 62833 | ||||||||||||
Collection: | CaltechAUTHORS | ||||||||||||
Deposited By: | Ruth Sustaita | ||||||||||||
Deposited On: | 14 Dec 2015 17:42 | ||||||||||||
Last Modified: | 10 Nov 2021 23:07 |
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