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Measurement of Anesthetic Potency

Fenichel, I. Robert and Horowitz, Samuel B. and Cherkin, Arthur and Catchpool, J. F. (1966) Measurement of Anesthetic Potency. Science, 152 (3725). pp. 1110-1111. ISSN 0036-8075. http://resolver.caltech.edu/CaltechAUTHORS:20151214-071458387

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Abstract

In "Temperature dependence of anesthesia in goldfish" (l), Cherkin and Catchpool introduce a technique for making quantitative measurements of the anesthetic potency of water-soluble agents. Goldfish are kept swimming by an applied stimulus (an electric shock); anesthetic potency is measured as AD_(50) the dose at which 50 percent of the experimental animals fail to respond to the stimulus.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1126/science.152.3725.1110 DOIArticle
http://www.sciencemag.org/content/152/3725/1110.extractPublisherArticle
http://www.jstor.org/stable/1718239JSTORArticle
Additional Information:© 1966 American Association for the Advancement of Science. 27 October 1965. Supported in part by NSF grant GB 3109 and PHS grant GM 11070.
Funders:
Funding AgencyGrant Number
NSFGB 3109
U.S. Public Health Service (USPHS)GM-11070
Record Number:CaltechAUTHORS:20151214-071458387
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20151214-071458387
Official Citation:Measurement of Anesthetic Potency I. Robert Fenichel, Samuel B. Horowitz, Arthur Cherkin, and J. F. Catchpool Science 20 May 1966: 152 (3725), 1110-1111. [DOI:10.1126/science.152.3725.1110]
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:62833
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:14 Dec 2015 17:42
Last Modified:14 Dec 2015 17:42

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