Measurement of Anesthetic Potency

Fenichel, I. Robert and Horowitz, Samuel B. and Cherkin, Arthur and Catchpool, J. F. (1966) Measurement of Anesthetic Potency. Science, 152 (3725). pp. 1110-1111. ISSN 0036-8075. doi:10.1126/science.152.3725.1110. https://resolver.caltech.edu/CaltechAUTHORS:20151214-071458387

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Abstract

In "Temperature dependence of anesthesia in goldfish" (l), Cherkin and Catchpool introduce a technique for making quantitative measurements of the anesthetic potency of water-soluble agents. Goldfish are kept swimming by an applied stimulus (an electric shock); anesthetic potency is measured as AD_(50) the dose at which 50 percent of the experimental animals fail to respond to the stimulus.

Item Type:

Article

Related URLs:

URL	URL Type	Description
http://dx.doi.org/10.1126/science.152.3725.1110	DOI	Article
http://www.sciencemag.org/content/152/3725/1110.extract	Publisher	Article
http://www.jstor.org/stable/1718239	JSTOR	Article

Additional Information:

Funders:

Funding Agency	Grant Number
NSF	GB 3109
U.S. Public Health Service (USPHS)	GM-11070

Issue or Number:

3725

DOI:

10.1126/science.152.3725.1110

Record Number:

CaltechAUTHORS:20151214-071458387

Persistent URL:

https://resolver.caltech.edu/CaltechAUTHORS:20151214-071458387

Official Citation:

Measurement of Anesthetic Potency I. Robert Fenichel, Samuel B. Horowitz, Arthur Cherkin, and J. F. Catchpool Science 20 May 1966: 152 (3725), 1110-1111. [DOI:10.1126/science.152.3725.1110]

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ID Code:

62833

Collection:

CaltechAUTHORS

Deposited By:

Ruth Sustaita

Deposited On:

14 Dec 2015 17:42

Last Modified:

10 Nov 2021 23:07

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