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Dscam and Neuronal Uniqueness

Zinn, Kai (2007) Dscam and Neuronal Uniqueness. Cell, 129 (3). pp. 455-456. ISSN 0092-8674. doi:10.1016/j.cell.2007.04.024.

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In the fruit fly Drosophila the gene encoding the cell adhesion molecule Dscam generates alternatively spliced mRNAs that can be translated into thousands of different protein isoforms. Three recent papers show that isoform-specific homophilic Dscam interactions cause dendritic branches of the same neuron to avoid each other (Hughes et al., 2007, Soba et al., 2007 and Matthews et al., 2007). This process ensures the correct patterning of dendrites in the peripheral nervous system.

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Zinn, Kai0000-0002-6706-5605
Additional Information:© 2007 Elsevier Inc.
Issue or Number:3
Record Number:CaltechAUTHORS:20151216-110333007
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Official Citation:Kai Zinn, Dscam and Neuronal Uniqueness, Cell, Volume 129, Issue 3, 4 May 2007, Pages 455-456, ISSN 0092-8674, (
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:62977
Deposited By: Tony Diaz
Deposited On:16 Dec 2015 19:50
Last Modified:10 Nov 2021 23:09

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