Smith, L. Courtney and Davidson, Eric H. (1992) The echinoid immune system and the phylogenetic occurrence of immune mechanisms in deuterostomes. Immunology Today, 13 (9). pp. 356-362. ISSN 0167-5699. doi:10.1016/0167-5699(92)90172-4. https://resolver.caltech.edu/CaltechAUTHORS:20151222-160437263
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Abstract
In this article, Courtney Smith and Eric Davidson reinterpret the published data on immune function in lower deuterostomes and primitive chordates. It leads them to a new model of immune system phylogeny in which MHC-directed T-cell responses are the last to evolve and are not derived from subchordate self-nonself recognition systems.
| Item Type: | Article | |||||||||
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| Additional Information: | © 1992 Elsevier Science Publishers Ltd, UK. We wish to thank Ellen Rothenberg of Caltech for insightful discussions of the ideas in this manuscript. We are grateful to Gary Littman of All Childrens Hospital, University of S. Florida and Charles Janeway of Yale University for their valuable comments. This work was supported by a Developmental Biology Grant from the Lucille P. Markey Charitable Trust. | |||||||||
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| Issue or Number: | 9 | |||||||||
| DOI: | 10.1016/0167-5699(92)90172-4 | |||||||||
| Record Number: | CaltechAUTHORS:20151222-160437263 | |||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20151222-160437263 | |||||||||
| Official Citation: | L.Courtney Smith, Eric H Davidson, The echinoid immune system and the phylogenetic occurrence of immune mechanisms in deuterostomes, Immunology Today, Volume 13, Issue 9, 1992, Pages 356-362, ISSN 0167-5699, http://dx.doi.org/10.1016/0167-5699(92)90172-4. (http://www.sciencedirect.com/science/article/pii/0167569992901724) | |||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | |||||||||
| ID Code: | 63160 | |||||||||
| Collection: | CaltechAUTHORS | |||||||||
| Deposited By: | Tony Diaz | |||||||||
| Deposited On: | 23 Dec 2015 19:46 | |||||||||
| Last Modified: | 10 Nov 2021 23:12 |
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