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The echinoid immune system and the phylogenetic occurrence of immune mechanisms in deuterostomes

Smith, L. Courtney and Davidson, Eric H. (1992) The echinoid immune system and the phylogenetic occurrence of immune mechanisms in deuterostomes. Immunology Today, 13 (9). pp. 356-362. ISSN 0167-5699. doi:10.1016/0167-5699(92)90172-4. https://resolver.caltech.edu/CaltechAUTHORS:20151222-160437263

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Abstract

In this article, Courtney Smith and Eric Davidson reinterpret the published data on immune function in lower deuterostomes and primitive chordates. It leads them to a new model of immune system phylogeny in which MHC-directed T-cell responses are the last to evolve and are not derived from subchordate self-nonself recognition systems.


Item Type:Article
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URLURL TypeDescription
http://dx.doi.org/10.1016/0167-5699(92)90172-4DOIArticle
http://www.sciencedirect.com/science/article/pii/0167569992901724PublisherArticle
Additional Information:© 1992 Elsevier Science Publishers Ltd, UK. We wish to thank Ellen Rothenberg of Caltech for insightful discussions of the ideas in this manuscript. We are grateful to Gary Littman of All Childrens Hospital, University of S. Florida and Charles Janeway of Yale University for their valuable comments. This work was supported by a Developmental Biology Grant from the Lucille P. Markey Charitable Trust.
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Funding AgencyGrant Number
Lucille P. Markey Charitable TrustUNSPECIFIED
Issue or Number:9
DOI:10.1016/0167-5699(92)90172-4
Record Number:CaltechAUTHORS:20151222-160437263
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20151222-160437263
Official Citation:L.Courtney Smith, Eric H Davidson, The echinoid immune system and the phylogenetic occurrence of immune mechanisms in deuterostomes, Immunology Today, Volume 13, Issue 9, 1992, Pages 356-362, ISSN 0167-5699, http://dx.doi.org/10.1016/0167-5699(92)90172-4. (http://www.sciencedirect.com/science/article/pii/0167569992901724)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:63160
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:23 Dec 2015 19:46
Last Modified:10 Nov 2021 23:12

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