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Tyrosine phosphorylation and axon guidance: of mice and flies

Desai, Chand J. and Sun, Qi and Zinn, Kai (1997) Tyrosine phosphorylation and axon guidance: of mice and flies. Current Opinion in Neurobiology, 7 (1). pp. 70-74. ISSN 0959-4388. doi:10.1016/S0959-4388(97)80122-5.

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Recent genetic evidence suggests that tyrosine kinases and tyrosine phosphatases can control the guidance of specific growth cones. Within a family of related phosphatases or kinases, individual members can have partially redundant functions. Receptor phosphatases can work together at one guidance choice point, but in opposition at another. The specific combination of kinases and phosphatases active in a growth cone may be an important determinant of pathway choice. One mechanism by which these proteins could control guidance decisions is through regulation of adhesion between growth cones and axons.

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Zinn, Kai0000-0002-6706-5605
Additional Information:© 1997 Current Biology Ltd. Funding in the authors' laboratory is from a National Institutes of Health (NIH) RO1 grant to K Zinn.
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Issue or Number:1
Record Number:CaltechAUTHORS:20151223-094603567
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Official Citation:Chang J Desai, Qi Sun, Kai Zinn, Tyrosine phosphorylation and axon guidance: of mice and flies, Current Opinion in Neurobiology, Volume 7, Issue 1, February 1997, Pages 70-74, ISSN 0959-4388, (
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:63171
Deposited By: Tony Diaz
Deposited On:23 Dec 2015 17:53
Last Modified:10 Nov 2021 23:12

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