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Lipopolysaccharide activates the sea urchin immune system

Smith, L. Courtney and Britten, Roy J. and Davidson, Eric H. (1995) Lipopolysaccharide activates the sea urchin immune system. Developmental and Comparative Immunology, 19 (3). pp. 217-224. ISSN 0145-305X. doi:10.1016/0145-305X(95)00009-I. https://resolver.caltech.edu/CaltechAUTHORS:20151223-141054015

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Abstract

Profilin is a small, actin-binding protein that functions at the intersection of signal transduction and cytoskeletal modifications. Increases in the number of profilin messages per cell correlate with sea urchin coelomocyte activation in response to injury. Here we show that coelomocytes respond to immune challenge from lipopolysaccharide with significant elevations in profilin transcripts per coelomocyte.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1016/0145-305X(95)00009-IDOIArticle
http://www.sciencedirect.com/science/article/pii/0145305X9500009IPublisherArticle
Additional Information:© 1995 Elsevier. (Submitted February 1995; accepted April 1995) The authors wish to acknowledge the useful comments of the anonymous reviewers. This work was supported by a grant from NSF (No. MCB 9219330).
Funders:
Funding AgencyGrant Number
NSFMCB-9219330
Subject Keywords:Sea urchin; Strongylocentrotus purpuratus; Coelomocyte activation; Profilin; LPS
Issue or Number:3
DOI:10.1016/0145-305X(95)00009-I
Record Number:CaltechAUTHORS:20151223-141054015
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20151223-141054015
Official Citation:L. Courtney Smith, Roy J. Britten, Eric H. Davidson, Lipopolysaccharide activates the sea urchin immune system, Developmental & Comparative Immunology, Volume 19, Issue 3, May–June 1995, Pages 217-224, ISSN 0145-305X, http://dx.doi.org/10.1016/0145-305X(95)00009-I. (http://www.sciencedirect.com/science/article/pii/0145305X9500009I)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:63200
Collection:CaltechAUTHORS
Deposited By: George Porter
Deposited On:26 Feb 2016 15:38
Last Modified:10 Nov 2021 23:13

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