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Maternal and embryonic provenance of a sea urchin embryo transcription factor, SpZ12-1

Wang, D. G. and Britten, R. J. and Davidson, E. H. (1995) Maternal and embryonic provenance of a sea urchin embryo transcription factor, SpZ12-1. Molecular Marine Biology and Biotechnology, 4 (2). pp. 148-153. ISSN 1053-6426.

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SpZ12-1 is a zinc-finger transcription factor. Previous work has indicated that this factor functions late in embryogenesis as a spatial transcriptional repressor. We show here that this factor is present in significant quantities even in unfertilized egg cytoplasm, and in similar quantities in mesenchyme blastula-stage embryo cytoplasm. Taken together with earlier measurements of Calzone and associates, our observations indicate that SpZ12-1 enters the embryonic nuclei between late cleavage and mesenchyme blastula stages. A low-prevalence mRNA encoding SpZ12-1 is also present throughout development. Translation of this mRNA could, however, easily account for the complete complement of SpZ12-1 protein in the embryo, as estimated from its DNA binding activity. SpZ12-1 probably functions at several developmental stages and is evidently of both maternal and embryonic provenance.

Item Type:Article
Additional Information:© 1995 Springer.
Issue or Number:2
Record Number:CaltechAUTHORS:20151223-141227669
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:63201
Deposited By: George Porter
Deposited On:24 Feb 2016 22:47
Last Modified:03 Oct 2019 09:26

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