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Developmental regulation of neurotransmitter phenotype

Black, Ira B. and Patterson, Paul H. (1980) Developmental regulation of neurotransmitter phenotype. In: Neural Development Part I: Emergence of Specificity in Neural Histogenesis. Current Topics in Developmental Biology. No.15. Academic Press , New York, NY, pp. 27-40. ISBN 0-12-153115-5.

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The extraordinary scope of neuronal plasticity has been appreciated only recently. The neuron is capable not only of altering structure and function quantitatively, but also of undergoing phenotypic transformation under appropriate circumstances. It is now well established from in vivo and in vitro studies that neurons may change transmitters, and thus phenotypes, during a relatively prolonged period of life. This, of course, has raised the possibility that neurons can change a variety of functions and capabilities, and that, for example, recovery after illness or regeneration after injury may be induced by appropriate treatments. In turn, a central issue in understanding the regulation of phenotypic expression in neurons, as well as other systems, concerns the relationship of intrinsic cellular information to environmental factors.

Item Type:Book Section
Additional Information:© 1980 Academic Press.
Series Name:Current Topics in Developmental Biology
Issue or Number:15
Record Number:CaltechAUTHORS:20151229-145035523
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:63250
Deposited By: George Porter
Deposited On:04 Feb 2016 16:20
Last Modified:03 Oct 2019 09:26

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