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Gene regulatory network controlling embryonic specification in the sea urchin

Oliveri, Paola and Davidson, Eric H. (2004) Gene regulatory network controlling embryonic specification in the sea urchin. Current Opinion in Genetics and Development, 14 (4). pp. 351-360. ISSN 1879-0380. doi:10.1016/j.gde.2004.06.004.

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The current state of the gene regulatory network for endomesoderm specification in sea urchin embryos is reviewed. The network was experimentally defined, and is presented as a predictive map of cis-regulatory inputs and functional regulatory gene interconnections (updated versions of the network and most of the underlying data are at The network illuminates the ‘whys’ of many aspects of zygotic control in early sea urchin development, both spatial and temporal. The network includes almost 50 genes, and these are organized in subcircuits, each of which executes a particular regulatory function.

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Additional Information:© 2004 Elsevier Ltd. Research was supported by National Institutes of Health grant HD37105 and by the Office of Science (BER), US Department of Energy, grant DE-FG02-03ER63584. P Oliveri was supported by the Camilla Chandler Frost Fellowship.
Funding AgencyGrant Number
Department of Energy (DOE)DE-FG02-03ER63584
Camilla Chandler Frost FellowshipUNSPECIFIED
Issue or Number:4
Record Number:CaltechAUTHORS:20160106-143628614
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Official Citation:Paola Oliveri, Eric H Davidson, Gene regulatory network controlling embryonic specification in the sea urchin, Current Opinion in Genetics & Development, Volume 14, Issue 4, August 2004, Pages 351-360, ISSN 0959-437X, (
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:63435
Deposited By: Tony Diaz
Deposited On:06 Jan 2016 22:40
Last Modified:10 Nov 2021 23:16

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