Neurotransmitter synthesis and uptake by isolated sympathetic neurones in microcultures

Reichardt, L. F. and Patterson, P. H. (1977) Neurotransmitter synthesis and uptake by isolated sympathetic neurones in microcultures. Nature, 270 (5633). pp. 147-151. ISSN 0028-0836. doi:10.1038/270147a0. https://resolver.caltech.edu/CaltechAUTHORS:20160113-114328187

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Abstract

Assays of isolated single sympathetic neurones show that their transmitter functions can be either adrenergic or cholinergic depending on growth conditions. The data suggest that the number of transmitters made by most mature individual neurones is restricted.

Item Type:

Article

Related URLs:

URL	URL Type	Description
http://dx.doi.org/10.1038/270147a0	DOI	Article
http://www.nature.com/nature/journal/v270/n5633/abs/270147a0.html	Publisher	Article

Additional Information:

© 1977 Nature Publishing Group. Received 31 May accepted 15 August 1977. We thank Drs Linda Chun, Philippa Claude, Edwin Furshpan, and David Potter for suggestions and for reagents, and Karen Fischer and Doreen McDowell for their aid in maintaining cultures. This work was supported by a Grant-in-Aid (93-877) from the American and Massachusetts Heart Associations and a USPHS grant (l ROI NS 11028) from the National Institute of Neurological and Communicable iseases and Stroke. P.H.P. is a Research Career Development Awardee of the NINCDS (I K04 NS70806) and L.F.R. was supported by fellowships from the Jane Coffin Childs Foundation, the Medical Foundation, and NINCDS.

Funders:

Funding Agency	Grant Number
U.S. Public Health Service (USPHS)	93-877
National Institute of Neurological and Communicable Diseases and Stroke (NINCDS)	1 RO1 NS 11028
National Institute of Neurological and Communicable Diseases and Stroke (NINCDS)	I K04 NS70806
Jane Coffin Childs Memorial Fund for Medical Research	UNSPECIFIED
Medical Foundation	UNSPECIFIED
American Heart Association	UNSPECIFIED
Massachusetts Heart Association	UNSPECIFIED

Issue or Number:

5633

DOI:

10.1038/270147a0

Record Number:

CaltechAUTHORS:20160113-114328187

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https://resolver.caltech.edu/CaltechAUTHORS:20160113-114328187

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No commercial reproduction, distribution, display or performance rights in this work are provided.

ID Code:

63635

Collection:

CaltechAUTHORS

Deposited By:

Ruth Sustaita

Deposited On:

13 Jan 2016 19:57

Last Modified:

10 Nov 2021 23:19

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