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Neurotransmitter synthesis and uptake by isolated sympathetic neurones in microcultures

Reichardt, L. F. and Patterson, P. H. (1977) Neurotransmitter synthesis and uptake by isolated sympathetic neurones in microcultures. Nature, 270 (5633). pp. 147-151. ISSN 0028-0836. https://resolver.caltech.edu/CaltechAUTHORS:20160113-114328187

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Abstract

Assays of isolated single sympathetic neurones show that their transmitter functions can be either adrenergic or cholinergic depending on growth conditions. The data suggest that the number of transmitters made by most mature individual neurones is restricted.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1038/270147a0DOIArticle
http://www.nature.com/nature/journal/v270/n5633/abs/270147a0.htmlPublisherArticle
Additional Information:© 1977 Nature Publishing Group. Received 31 May accepted 15 August 1977. We thank Drs Linda Chun, Philippa Claude, Edwin Furshpan, and David Potter for suggestions and for reagents, and Karen Fischer and Doreen McDowell for their aid in maintaining cultures. This work was supported by a Grant-in-Aid (93-877) from the American and Massachusetts Heart Associations and a USPHS grant (l ROI NS 11028) from the National Institute of Neurological and Communicable iseases and Stroke. P.H.P. is a Research Career Development Awardee of the NINCDS (I K04 NS70806) and L.F.R. was supported by fellowships from the Jane Coffin Childs Foundation, the Medical Foundation, and NINCDS.
Funders:
Funding AgencyGrant Number
U.S. Public Health Service (USPHS)93-877
National Institute of Neurological and Communicable Diseases and Stroke (NINCDS)1 RO1 NS 11028
National Institute of Neurological and Communicable Diseases and Stroke (NINCDS)I K04 NS70806
Jane Coffin Childs Memorial Fund for Medical ResearchUNSPECIFIED
Medical FoundationUNSPECIFIED
American Heart AssociationUNSPECIFIED
Massachusetts Heart AssociationUNSPECIFIED
Issue or Number:5633
Record Number:CaltechAUTHORS:20160113-114328187
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20160113-114328187
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:63635
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:13 Jan 2016 19:57
Last Modified:03 Oct 2019 09:30

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