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Neural expression of mouse Noelin-1/2 and comparison with other vertebrates

Moreno, Tanya A. and Bronner-Fraser, Marianne (2002) Neural expression of mouse Noelin-1/2 and comparison with other vertebrates. Mechanisms of Development, 119 (1). pp. 121-125. ISSN 0925-4773. doi:10.1016/S0925-4773(02)00308-8.

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Noelins are secreted glycoproteins with important developmental functions in frogs and birds. Here, we present the expression pattern of the mouse homolog of Noelin-1/2 at E8–10 of development and compare this pattern to other vertebrates. Expression was observed in the neural plate and neural crest, as well as in the cranial ganglia. Later, expression is prominent in brain tissue and in the zone of polarizing activity in the limb.

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Bronner-Fraser, Marianne0000-0003-4274-1862
Additional Information:© 2002 Elsevier Science Ireland Ltd. Received 11 April 2002; received in revised form 31 May 2002; accepted 31 May 2002. The authors wish to thank Anne Knecht and Clare Baker for reading the manuscript and Meyer Barembaum for providing photographs of chick Noelin-1/2 expression for Fig. 4. T.A.M. is a Fellow of the ARCS foundation. This work was supported by grant NS42287 to M.B.-F.
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Subject Keywords:Mouse; Noelin; Neural crest; Neural plate; Cranial placodes; Cranial ganglia
Issue or Number:1
Record Number:CaltechAUTHORS:20160122-105357540
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Official Citation:Tanya A. Moreno, Marianne Bronner-Fraser, Neural expression of mouse Noelin-1/2 and comparison with other vertebrates, Mechanisms of Development, Volume 119, Issue 1, November 2002, Pages 121-125, ISSN 0925-4773, (
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:63895
Deposited By: Ruth Sustaita
Deposited On:25 Jan 2016 17:41
Last Modified:10 Nov 2021 23:22

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