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Probing DNA charge transport with metallointercalators

Núñez, Megan E. and Barton, Jacqueline K. (2000) Probing DNA charge transport with metallointercalators. Current Opinion in Chemical Biology, 4 (2). pp. 199-206. ISSN 1367-5931. https://resolver.caltech.edu/CaltechAUTHORS:20160129-080803438

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Abstract

A wide range of experiments have emerged recently regarding charge transport through DNA, including spectroscopic studies of rates of DNA-mediated electron transfer and biochemical studies of DNA base oxidation over long distances. These experiments have, in turn, led to new proposals about the way in which charge moves through DNA and have prompted the consideration of physiological roles for DNA electron transfer. Importantly, metallointercalators have been key players in many of these experiments. Metallointercalators provide critical probes to examine the migration of charge through the DNA base stack.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1016/S1367-5931(99)00075-7DOIArticle
http://www.sciencedirect.com/science/article/pii/S1367593199000757PublisherArticle
ORCID:
AuthorORCID
Barton, Jacqueline K.0000-0001-9883-1600
Additional Information:© 2000 Elsevier Science Ltd. Available online 27 April 2000. We are grateful to the National Institutes of Health (GM49216) for their financial support. We are grateful also to our colleagues and collaborators whose work is described here.
Funders:
Funding AgencyGrant Number
NIHGM49216
Subject Keywords:DNA charge transport; Metallointercalators; Electron transfer; Thymine-dimer repair
Issue or Number:2
Record Number:CaltechAUTHORS:20160129-080803438
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20160129-080803438
Official Citation:Megan E Núñez, Jacqueline K Barton, Probing DNA charge transport with metallointercalators, Current Opinion in Chemical Biology, Volume 4, Issue 2, 1 April 2000, Pages 199-206, ISSN 1367-5931, http://dx.doi.org/10.1016/S1367-5931(99)00075-7. (http://www.sciencedirect.com/science/article/pii/S1367593199000757)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:64077
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:29 Jan 2016 16:59
Last Modified:03 Oct 2019 09:34

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