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Alfred Gilman (1941-2015)

Simon, Melvin (2016) Alfred Gilman (1941-2015). Science, 351 (6273). p. 566. ISSN 0036-8075. http://resolver.caltech.edu/CaltechAUTHORS:20160222-083411138

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Abstract

Alfred Goodman Gilman died on 23 December, after a protracted battle with pancreatic cancer. We lost an extraordinary scientist, academic leader, and “mensch.” Al pioneered our understanding of the biochemical mechanisms that drive signal transduction and (with Martin Rodbell) shared the 1994 Nobel Prize in Physiology or Medicine for his role in the discovery of heterotrimeric guanine nucleotide-binding proteins (G proteins). He went on to describe the basic design of G protein-mediated cellular signaling circuits that regulate an enormous number of physiological responses and are the targets of a large fraction of today's drugs.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1126/science.aaf2848DOIArticle
http://science.sciencemag.org/content/351/6273/566PublisherArticle
Additional Information:© 2016 American Association for the Advancement of Science.
Record Number:CaltechAUTHORS:20160222-083411138
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20160222-083411138
Official Citation:Alfred Gilman (1941–2015) BY MELVIN SIMON Science 05 Feb 2016: Vol. 351, Issue 6273, pp. 566 DOI: 10.1126/science.aaf2848
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:64621
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:22 Feb 2016 18:10
Last Modified:22 Feb 2016 18:10

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