Sahani, Maneesh and Pezaris, John S. and Andersen, Richard A. (1998) On the Separation of Signals from Neighboring Cells in Tetrode Recordings. In: Advances in Neural Information Processing Systems 10 (NIPS 1997). Advances in Neural Information Processing Systems. No.10. MIT Press , Cambridge, MA, pp. 222-227. ISBN 0-262-10076-2. https://resolver.caltech.edu/CaltechAUTHORS:20160224-144314552
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Abstract
We discuss a solution to the problem of separating waveforms produced by multiple cells in an extracellular neural recording. We take an explicitly probabilistic approach, using latent-variable models of varying sophistication to describe the distribution of waveforms produced by a single cell. The models range from a single Gaussian distribution of waveforms for each cell to a mixture of hidden Markov models. We stress the overall statistical structure of the approach, allowing the details of the generative model chosen to depend on the specific neural preparation.
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Additional Information: | © 1998 Massachusetts Institute of Technology. This work has benefited considerably from important discussions with both Bill Bialek and Sam Roweis. John Hopfield has provided invaluable advice and mentoring to MS. We thank Jennifer Linden and Philip Sabes for useful comments on an earlier version of the manuscript. Funding for various components of the work has been provided by the Keck Foundation, the Sloan Center for Theoretical Neuroscience at Caltech, the Center for Neuromorphic Systems Engineering at Caltech, and the National Institutes of Health. | ||||||||||||
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Series Name: | Advances in Neural Information Processing Systems | ||||||||||||
Issue or Number: | 10 | ||||||||||||
Record Number: | CaltechAUTHORS:20160224-144314552 | ||||||||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20160224-144314552 | ||||||||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||||
ID Code: | 64744 | ||||||||||||
Collection: | CaltechAUTHORS | ||||||||||||
Deposited By: | INVALID USER | ||||||||||||
Deposited On: | 24 Feb 2016 22:48 | ||||||||||||
Last Modified: | 09 Mar 2020 13:18 |
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