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Conservation of Pax gene expression in ectodermal placodes of the lamprey

McCauley, David W. and Bronner-Fraser, Marianne (2002) Conservation of Pax gene expression in ectodermal placodes of the lamprey. Gene, 287 (1-2). pp. 129-139. ISSN 0378-1119. doi:10.1016/S0378-1119(01)00894-0. https://resolver.caltech.edu/CaltechAUTHORS:20160302-071129792

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Abstract

Ectodermal placodes contribute to the cranial ganglia and sense organs of the head and, together with neural crest cells, represent defining features of the vertebrate embryo. The identity of different placodes appears to be specified in part by the expression of different Pax genes, with Pax-3/7 class genes being expressed in the trigeminal placode of mice, chick, frogs and fish, and Pax-2/5/8 class genes expressed in the otic placode. Here, we present the cloning and expression pattern of lamprey Pax-7 and Pax-2, which mark the trigeminal and otic placodes, respectively, as well as other structures characteristic of vertebrate Pax genes. These results suggest conservation of Pax genes and placodal structures in basal and derived vertebrates.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1016/S0378-1119(01)00894-0DOIArticle
http://www.sciencedirect.com/science/article/pii/S0378111901008940PublisherArticle
ORCID:
AuthorORCID
Bronner-Fraser, Marianne0000-0003-4274-1862
Additional Information:© 2002 Elsevier Science B.V. Received 27 August 2001; received in revised form 4 December 2001; accepted 12 December 2001. Available online 15 March 2002. Received by R. Di Lauro. We thank Roger Bergstedt and the staff of Hammond Bay Biological Station and Dr. Jim Langeland for assistance in collection of embryos, Burcu Babaoglan for assistance with LampPax-2 in situs and library screening, and Dan Meulemans for excellent technical assistance. This work was supported by NASA grant 98-HEDS-02 to MBF.
Funders:
Funding AgencyGrant Number
NASA98-HEDS-02
Subject Keywords:Ectodermal placode; Gene expression; Pax-7; Pax-2; Conservation
Issue or Number:1-2
DOI:10.1016/S0378-1119(01)00894-0
Record Number:CaltechAUTHORS:20160302-071129792
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20160302-071129792
Official Citation:David W McCauley, Marianne Bronner-Fraser, Conservation of Pax gene expression in ectodermal placodes of the lamprey, Gene, Volume 287, Issues 1–2, 3 April 2002, Pages 129-139, ISSN 0378-1119, http://dx.doi.org/10.1016/S0378-1119(01)00894-0. (http://www.sciencedirect.com/science/article/pii/S0378111901008940)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:64942
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:02 Mar 2016 18:18
Last Modified:10 Nov 2021 23:37

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